As part of the 1995 National Science Foundation Systematic Change Initiative in Chemistry, two groups developed a complementary set of modules focusing on real-world problems as a way to introduce important core concepts, show the links between chemistry and other disciplines, and create a flexible model for curriculum reform (http://www.nsf.gov/news/news_summ.jsp?cntn_id=100783). Presenters in this Symposium will consider (1) how the topical modules and their use have changed over time, (2) what active learning strategies have persisted, (3) what resources derived from these initiatives are available for use in classes, and (4) the impact of involvement on the subsequent professional work of participants.